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betadglucan biomarkers cardiomyopathy comparison echocardiogram fungal galactomannan hcm hemophagocytic hlh hocm hypertrophic lymphohistiocytosis management plax pocus rheumatology septal summary treatment
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Other positives ... infection (IFI) in hematologic ... cut-offs defined in clinical ... - Frozen ice-pops ... Galactomannan #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU
Septal Hypertrophic Cardiomyopathy (HOCM) 52yo worsening exertional sx and murmur. EKG nonspecific, Serial trops (-) EM resident
Serial trops (-) EM ... Admit ==> Positive ... Metoprolol - VCU ... Cardiomyopathy #HOCM #HCM #clinical ... echocardiogram #plax #cardiology
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