11 results
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
Her clinical exam ... non-localized EOM ... cogan sign and the ice ... #PhysicalExam #clinical ... ophthalmology #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... myasthenia Diagnosis ... Bedside: ice pack ... #diagnosis #management ... #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
suspect 2️⃣ How to Diagnose ... When to admit to ICU ... 5️⃣ Treatment ... complications 8️⃣ Clinical ... Syndrome #Management #Neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... : • Based on clinical ... antibodies - MuSK-positive ... #Myasthenia #Gravis ... #neurology #treatment
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
virus • CMV • EBV ... • Common clinical ... • Gram stain: Positive ... 90% • Culture: Positive ... #neurology #meningitis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- HIV, CMV, EBV ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #management #treatment ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... and cauda equina TREATMENT ... specific therapy, the clinician ... intensive care unit (ICU ... #management #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... Antimicrobial treatment ... effect/Edema • EBV ... and <25% culture positive ... InfectiousDiseases #Neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Brucellosis - Dengue, EBV ... Transverse Myelitis Treatment ... #management #neurology