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clinical cullensign em emergencymedicine fm hemophagocytic hlh im image lymphohistiocytosis management pancreatitis peritonitis rheumatology summary surgery treatment
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Diagnosis and Context ... sign is not diagnostic ... important in the diagnostic ... #cullensign #em ... peritonitis #IM #FM #ICU
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Ferritin >1000 ng ... Infections+++: Virus (EBV ... biologics (CMV +++, EBV ... of emergency, ICU
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