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diagnosis management gout infectiousdiseases treatment aids arthritis aspergillus autoimmune betadglucan biomarkers cppd debridement erythematosus galactomannan hiv infection lung lupus monoarthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... tuberculosis) • Fungi ... #pain #Differential
Pediatrics Sepsis Screening SIGNS OF INFECTION? • Fever (>38C) • Hypothermia (<36C) • Cough/chest pain/respiratory distress •
Pediatrics Sepsis ... • Fever (>38C) ... diarrhea • Skin/joint ... RISK MEDICAL CONDITIONS ... • Other high-risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... useful in high risk ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... MUCORMYCOSIS • Risk ... • Cough, fever ... muscle aches, joint ... Encapsulated yeast • At risk
Debridement and Management of Prosthetic Joint Infection (PJI) Duration of symptoms <3 weeks OR <30 days
of Prosthetic Joint ... Staphylococci: 24wk for knees ... DDIs/AEs) - Fungus ... whether benefit > risk ... - Never “lifelong
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... #CPPD #Gout #Comparison ... #rheumatology #
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... • CT: Halo sign ... Pneumonia: • Risk
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... Diagnose concomitant infection ... drug failure • Risk
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... fibromyalgia) • Infections ... Arthritis: • Joint ... Thrombosis highest risk
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
disease Malignancy Risk ... and increased risk ... dermatomyositis) Malignancy Risk ... and increased risk ... and increased risk
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