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diagnosis rheumatology differential dermatology cryoglobulins cutaneous dermatologic erythematosus glomerulonephritis granulomatosis lupus polyangiitis progressive rapidly rpgn skin sle systemic types vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... (C-ANCA): GPA > ... GPA Stanford Internal ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... mucositis - Rash ... and branches • GCA ... (Dx: GPA, EGPA, ... #classification
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Urticarial/LCV) - Cryoglobulinemic ... ANCA Associated: ... - GPA Cutaneous ... : • Temporal arteritis ... • Takayasu's arteritis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... diagnosis #types #classification ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... #Polyangiitis #GPA ... #dermatology #rash
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Elevated ESR and CRP GCA ... develop in pts with GCA ... , mucositis • Rash ... MPO > PR3 60/ GPA ... + MPO) Cryoglobulinemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... vein thrombosis Hematologic ... anti-Ro/SSA can rule
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