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management algorithm differential elevatedmcv macrocytosis alkaline alp anorexianervosa aplastic classification common complications crisis cvid gammopathies hepatology hodgkins hyophosphatasia hypogammaglobulinemia immunodeficiency
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Serum B12 - Anti-IF ... - Low Serum B12 ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... with Low Mean Corpuscular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... Involved: uninvolved serum ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Low serum IgG ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... may result from low ... #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Blood Count - Low ... may be high or low ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
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