18 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
- Serum to Ascites ... oncotic pressure Low ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG ... Ascites #Fluid #Serum
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
pressure - Normal/low ... - Absent Serum ... albumin - Low ... albumin - Normal ... #Diagnosis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) ... - Differential Diagnosis ... Mixed ascites" Low ... #hepatology
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Ascites - Diagnosis ... and Management ... protein, culture • Serum-ascites-albumin-gradient ... (SAAG): > 1.1 g ... #Hepatology #SAAG
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
: • Low serum IgG ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum ... Hyophosphatasia #hepatology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... albumin - Assess ... infections are common causes ... testing #workup #diagnosis ... nephrotic #nephritic #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
Hepatic Hydrothorax
 • Presents as right sided in 85% of cases
 • Fluid studies:
sided in 85% of cases ... fluid albumin gradient ... may develop • Management ... #Hydrothorax #diagnosis ... #hepatology #pulmonary
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... albumin - Assess ... infections are common causes ... disease #workup #diagnosis ... initial #testing #nephrology