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management differential algorithm anemia blood classification elevatedmcv hepatology macrocytosis neurology product reactions syndrome treatment vasculitis adjusted age alkaline alp antinxp2
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Serum B12 - Anti-IF ... Serum B12 - Anti-IF ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... with Low Mean Corpuscular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low ... #differential #diagnosis ... #algorithm #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... : • Low serum IgG ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum ... Hyophosphatasia #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
protease activity - A low ... activity is the diagnostic ... If the value is low ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... factor level • Low ... classification #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... #rheumatology # ... cerebritis #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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