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differential algorithm management classification elevatedmcv macrocytosis oncology alkaline alp approach arthritis common comparison cvid deficiency disease druginduced folate folicacid hemolysis
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... • Increased Serum ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Serum B12 - Anti-IF ... - Low Serum B12 ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... with Low Mean Corpuscular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... MCV, MCH, MCHC, Serum ... Disorder • RBC Metabolism ... #Algorithm #Causes ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • Pernicious anemia ... Nephrolithiasis • Metabolic ... Phosphatase: • Other causes ... • Elevation of serum
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Low serum IgG ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
have hemolytic anemia ... folate that can cause ... stores with normal serum ... #differential #diagnosis ... #hematology #nutrition
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... protein) to exclude metabolic ... chest wall, and low ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... sle #comparison #table ... #rheumatology # ... diagnosis #management
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