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diagnosis management syndrome differential vasculitis capillary clarksons classification cryofibrinogenemia dermatology disease gca giantcell leak sapho signs sjogrens symptoms temporal timeline
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... arteries • Secondary ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Involves large and medium ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... identifies 85 to 95% of cases ... them, but urgent rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... , obstructive pulmonary ... + MPO-ANCA MEDIUM ... aortic aneurysm • Medium ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... primary condition MEDIUM ... tract, and often causes ... arthritis. ... Differential #Diagnosis #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... joint and spine, & medium ... Rule out other causes ... antiinflammatory properties e.g ... SAPHO #Syndrome #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... amyloidosis, PAH ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... , Median age 50 ... tissues: Myalgia, paresthesia ... filling +++ (risk of pulmonary ... timeline #treatment #rheumatology
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