11 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... antimicrobials, clinical ... but important causes ... antiphospholipid syndrome ... specific pathogens also
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 cases ... response preceding infection ... Clinical Features ... management #treatment #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
with previously stable ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs ... , and Guillain-Barre
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... to a preceding infection ... • Most common infection ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
by: • Headache ... status • Headache ... may precede the neurologic ... edema visualized as ... the underlying cause
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... Autoimmune (SLE/APLS ... : Serial negative ... in up to 30% of cases ... Marantic #diagnosis #table
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... Serologic and EMG ... - Peek sign ... precipitated by: Drugs, infection ... diagnosis #management #neurology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
evaluation should also ... Infection or cancer ... disruption ○ Otitis media ... II ○ Susac’s syndrome ... Labyrinthitis ○ Epstein-Barr
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Involves large and medium ... Diagnosis = clinical ... vasculitis vs infection ... claudication, headaches
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... primary condition MEDIUM ... tract, and often causes ... , recent viral infection ... aneurysms can also