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oncology algorithm generalized pruritus systemic aplastic dermatologic gpa granulomatosis management mds myelodysplasia polyangiitis primary rash syndromes thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Chronic myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
/ Systemic == Blood ... • Lymphoma • Leukemia ... Throbocythemia • Myelodisplastic ... Pruritus #primary #secondary ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Blood Glucose ... • Lymphoma • Leukemia ... #generalized #dermatology ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Causes • Anemia ... #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... and petechiae Causes ... result from low blood ... #oncology #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... surfaces of the joints ... Polyangiitis #GPA #dermatology ... #rheumatology
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