12 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... #Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Post-splenectomy Primary ... #Diagnosis #Causes ... #hematology #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary ... == Blood Glucose ... • Lymphoma • Leukemia ... #secondary #systemic ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Blood Glucose ... #generalized #dermatology ... #causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /Quantity: • Primary ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... - infiltrates (anemia ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... surfaces of the joints ... Polyangiitis #GPA #dermatology ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... Primary (essential ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... Viral Infection Clinical ... younger pts) Differential ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... CausesAnemia ... count with differential ... #hematology #oncology