9 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Ig A vasculitis ... - GPA - EGPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome • Vasculitis ... Sarcoidosis #dermatology ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... and branches • GCA ... • ANCA (Dx: GPA ... differential #diagnosis ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Infection - Vasculitis ... RA, Sjogren's, GPA ... #Diagnosis #Algorithm ... #Causes #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... Elevated ESR and CRP GCA ... develop in pts with GCA ... Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... diagnosis = vasculitis ... systemic complaints- anemia ... required due to skip ... them, but urgent rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... Malignancy (e.g. hematologic ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Rheumatology