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management classification algorithm arthropathies arthropathy bee cryoglobulinemia cryoglobulins disorders erythematosus hematology monoarthritis monoarticular monoclonal msk neurology oncology paraproteinemias polyarthritis polyarticular
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
an underlying autoimmune ... and treatment can ... • Systemic lupus ... polychondritis • Behcet ... #differential #
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... arthritis - with the skin ... autoimmune disease ... Lupus - with Systemic ... (SLE), should have
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... permanent alopecia Differential ... rheumatologic diseases ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Behçet Syndrome ... : - Ocular inflammatory ... Diagnosis: Systemic ... differential #diagnosis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... ) • Cutaneous Lesions ... disease) Differential ... #Syndrome #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... diseases: - 10% ... Henoch-Schönlein purpura) • Cutaneous ... lupus erythematosus ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... as SLE, atherosclerotic ... • Behcet syndrome ... #Differential #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ) • Cutaneous vasculitis ... Vasculitis: • ... Adenocarcinoma Treatment ... #Rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cartilage in the body (Autoimmune ... • Inner ear • Skin ... cases such as: • SLE ... Sarcoidosis • Behcet ... affected tissue Treatment
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