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differential vasculitis rash cryofibrinogenemia dermatologic glomerulonephritis gpa granulomatosis hematology petechiae petechial physicalexam polyangiitis progressive rapidly rpgn types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable purpura ... IgA vasculitis (Henoch-Schönlein ... purpura) • Cutaneous ... #classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Petechiae, Palpable purpura ... Petechiae • Palpable purpura ... Vesicles overlying purpuric ... polyangiitis • EGPA • Henoch-Schönlein ... purpura • Mixed
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... IgA nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
infection - RMSF - Henoch ... Schonlein Purpura ... Non-Palpable Rash: - Purpura ... • Skin biopsy ... #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: • Purpura ... Schonlein Purpura ... erythematous nodules, purpura ... scleritis • Palpable purpura ... causing palpable purpura
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
necrosis • Purpura ... Cryofibrinogenemia Diagnosis ... • Negative causes ... #rheumatology # ... hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura ... scleritis • Palpable purpura ... Schonlein Purpura ... ) • Palpable purpura ... macules, palpable purpura
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