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differential rheumatology vasculitis rash algorithm glomerulonephritis canimorsus capnocytophaga clinical cryoglobulins dermatologic granulomatosis hematology joint nephrology nonpalpable pain palpable petechiae petechial
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
ANCA: • C-ANCA: GPA ... • ↓C4: Lupus, Cryoglobulinemia ... IgA Nephropathy, Henoch ... Schonlein Purpura ... #nephrology #causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Lupus Nephritis, Cryoglobulinemia ... IgA nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Differential Diagnosis ... • Henoch-Schönlein ... cryoglobulinemia ... #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Skin ulcers ... Cryoglobulins Cause ... IgA vasculitis (Henoch-Schönlein ... #types #classification
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... purple, hemorrhagic skin ... vasculitis/HSP • Cryoglobulinemia ... #Differential #Diagnosis ... #nonpalpable #dermatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #differential #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
infection - RMSF - Henoch ... Schonlein Purpura ... RA, Sjogren's, GPA ... cryoglobulins • Skin ... #dermatology #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often present • Henoch ... Schonlein Purpura ... tract, and often causes ... • ANCA (Dx: GPA ... #rheumatology #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
MPO > PR3 60/ GPA ... often present) Henoch ... Schonlein Purpura ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
inoculate into soft ... +purpuric rash → ... the key to the diagnosis ... #Rash #dermatology ... #clinical #photo
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