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differential classification rash cryoglobulinemia cryoglobulins dermatologic glomerulonephritis granulomatosis management nutrition pathophysiology petechiae physicalexam polyangiitis progressive rapidly rpgn scurvy types vasculitides
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #algorithm #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Findings: • Petechiae ... • Henoch-Schönlein ... #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin ... #Algorithm #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... - GPA, EGPA, microscopic ... • IgA vasculitis ... (Henoch-Schönlein ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... tract, and often causes ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
often present) Henoch ... Schonlein Purpura ... (IgA Vasculitis ... tract, and often causes ... #Rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... • Petechiae, purpura ... , or any other cause ... periodontitis • ITP • Henoch-Schonlein ... Pathophysiology #VitaminC #AscorbicAcid
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