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Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
(GPA) Skin involvement ... , Palpable purpura ... • Palpable purpura ... • EGPAHenoch-Schönlein ... GPA #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... triad of Palpable ... polyangiitis ... • IgA vasculitis ... (Henoch-Schönlein
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
often present) Henoch ... Schonlein Purpura ... skin) • Palpable ... purpura, joint ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
• Microscopic Polyangiitis ... often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... vesicular eruption - Joints