6 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
associated vasculitis - GPA ... • IgA vasculitis ... (Henoch-Schönlein ... diagnosis #types #classification ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... infection - RMSF - Henoch ... Schonlein Purpura ... • Skin biopsy ... #Causes #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... reticularis Differential ... • Henoch-Schönlein ... cryoglobulinemia ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... tract, and often causes ... #classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
MPO > PR3 60/ GPA ... often present) Henoch ... Schonlein Purpura ... tract, and often causes ... #Diagnosis #Rheumatology