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differential vasculitis classification rash causes cryoglobulinemia cryoglobulins dermatologic granulomatosis joint pain petechiae petechial physicalexam polyangiitis progressive rapidly rashes rpgn types
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Petechiae, Palpable ... • Petechiae • Palpable ... • Henoch-Schönlein ... pneumonia with glomerulonephritis ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... #differential #diagnosis ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Algorithm Pinpoint ... infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin ... #dermatology #physicalexam
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Glomerulonephritis ... Clinical triad of Palpable ... associated vasculitis - GPA ... • IgA vasculitis ... (Henoch-Schönlein
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
MPO > PR3 60/ GPA ... often present) Henoch ... Schonlein Purpura ... skin) • Palpable ... #Rheumatology
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