11 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... - GPA Cutaneous ... #Vasculitis #skin ... #dermatology #rheumatology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura ... (HSP, IgA Vasculitis ... #Purpura #Henoch ... #IgA #Vasculitis ... #dermatology #skin
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
burning sensation or pain ... • Henoch-Schönlein ... cryoglobulinemia ... #dermatology #rash ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Henoch Schönlein ... purpuraPAN ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Vasculitis ... • Ig A vasculitis ... - GPA - EGPA ... #hematology #rheumatology ... #dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- GPA, EGPA, microscopic ... • IgA vasculitis ... (Henoch-Schönlein ... purpura) • Cutaneous ... classification #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... Vasculitis (Henoch-Schönlein ... - Symmetric palpable ... patients : abdominal pain ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often present • Henoch ... Schonlein Purpura ... (IgA vasculitis ... Vasculitis - Skin ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
lesions • Severe pain ... infection - RMSF - Henoch ... Schonlein Purpura ... cryoglobulins • Skin ... #dermatology #physicalexam