7 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... purpura (16%) ... Diagnosis: Vasculitis ... • Henoch-Schönlein ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... OF PALPABLE PURPURA ... • Ig A vasculitis ... Diagnosis #hematology ... palpable #nonpalpable
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Schonlein Purpura ... (IgA vasculitis ... Vasculitis - Skin ... differential #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... purpura, Arthralgia ... • IgA vasculitis ... (Henoch-Schönlein ... purpura) • Cutaneous
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... Schonlein Purpura ... ) • Palpable purpura ... Diagnosis #Rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Infection - Vasculitis ... Schonlein Purpura ... Rash: - Purpura ... #Causes #dermatology