9 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... • Henoch-Schönlein ... #dermatology #rash ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #algorithm #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... OF PALPABLE PURPURA ... #hematology #rheumatology ... #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential Diagnosis ... Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... Urticarial/LCV) - Cryoglobulinemic ... #dermatology #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
purpura • Hypersensitivity ... Schönlein purpura ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... purpura, Arthralgia ... (Henoch-Schönlein ... purpura) • Cutaneous ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Schonlein Purpura ... Rash: - Purpura ... cryoglobulins • Skin ... #Algorithm #Causes ... #dermatology #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... Schonlein Purpura ... skin) • Palpable ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Schonlein Purpura ... purpura: strong ... purpura. ... #rheumatology #