8 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... purpura, Arthralgia ... • IgA vasculitis ... (Henoch-Schönlein ... purpura) • Cutaneous
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
OF PALPABLE PURPURA ... : Vasculitis: ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #hematology #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... Glomerulonephritis #Vasculitis ... #algorithm #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) ... purpura • Vesicles ... overlying purpuric ... polyangiitis • EGPA • Henoch-Schönlein ... purpura • Mixed
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Schonlein Purpura ... (IgA vasculitis ... Vasculitis - Skin ... purpura.
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... Schonlein Purpura ... Rash: - Purpura ... - Autoimmune Vasculitis ... #Algorithm #Causes
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... necrosis • Purpura ... • Negative causes ... #diagnosis #rheumatology ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Purpura, ischemic ... Schonlein Purpura ... (IgA Vasculitis ... skin) • Palpable ... ) • Palpable purpura