8 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Petechiae, Palpable purpura ... • Henoch-Schönlein ... purpura • Mixed ... #dermatology #rash ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Petechiae, Palpable purpura ... : - Ig A (HSP) ... - GPA Cutaneous ... #skin #dermatology ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... • Ig A vasculitis ... /HSPCryoglobulinemia ... #hematology #rheumatology ... #nonpalpable #dermatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Vasculitis (Henoch-Schönlein ... Purpura) - French ... Symmetric palpable purpura ... #HSP #Diagnosis ... #Rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable purpura ... (Henoch-Schönlein ... purpura) • Cutaneous ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Schonlein Purpura ... (IgA vasculitis ... causing palpable purpura ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Purpura, ischemic ... Schonlein Purpura ... purpura, joint ... ) • Palpable purpura ... #Rheumatology