9 results
Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
Algorithm for Diagnosis ... Endocarditis, Henoch-SchönIein ... #Purpuric #Petechiae ... #Algorithm #Diagnosis ... #Dermatology #Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
, Palpable purpura ... • Palpable purpura ... • Henoch-Schönlein ... purpura • Mixed ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... IgA nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... - GPA Cutaneous ... #dermatology #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
infection - RMSF - Henoch ... Schonlein Purpura ... Non-Palpable Rash: - Purpura ... cryoglobulins • Skin ... #dermatology #physicalexam
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
disease Palpable purpura ... vasculitis • Henoch ... Schönlein purpura ... Sarcoidosis • GPA ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... triad of Palpable purpura ... IgA vasculitis (Henoch-Schönlein ... purpura) • Cutaneous ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Schonlein Purpura ... erythematous nodules, purpura ... scleritis • Palpable purpura ... causing palpable purpura
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... scleritis • Palpable purpura ... Schonlein Purpura ... ) • Palpable purpura ... macules, palpable purpura