21 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... Scl70 (in some cases ... Antinuclear #Antibody #Testing ... #differential # ... diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... , Drug-induced Lupus ... Sjogren's Syndrome (SS ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody Testing ... : • SjS, SLE, DM ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... annular rash on ... and aPL) 9) Unexplained ... erythematosus #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Patterns and Associated ... Sjogren's Syndrome (SS ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... Auto-Antibodies: - ANA ... - Anti-B2GP1 (aPL ... Diagnosis and Lupus ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... Diagnosis Algorithm ... Autoimmune Vasculitis (lupus ... : - ITP - APLS ... Diagnosis #Algorithm
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... Cytoplasmic Patterns ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis ... #Rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... Diagnosis Algorithm ... Christmas tree pattern ... #Diagnosis #Algorithm ... #causes