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hematology disease aosd blood hemophagocytic lymphohistiocytosis product reactions activation adult adultonset antinxp2 antinxp2dm dermatology dermatomyositis diagnossi fungal gastroenterology hemochromatosis hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... testing for HLH-associated ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... maculopapular rash ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... +, Adult-onset Still ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology # ... management
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
and Management ... Criteria - Fever lasting ... Polymorphous rash ... KD #vasculitis #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... elevated, HFE gene testing ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... maculopapular rash ... false negatives on testing ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... or anti-HNA Ab) ... false negatives on testing ... #Transfusion #diagnosis ... #management #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... (blue-purple) rash ... • Erythematous rash ... positive patients Treatment ... #management #rheumatology
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