8 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... - Nuclear and Cytoplasmic ... #Nuclear #Cytoplasmic ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... Cytoplasmic Patterns ... #Cytoplasmic #Patterns ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody Testing ... Speckled pattern: • SjS ... Raynaud phenomenon, SjS ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Pathogenesis: Unclear ... maculopapular rash ... ferritin, arthritis and ... Disease #AOSD #rheumatology ... #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... ANA Labs: • ↑ESR ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Conjunctivitis, Mucositis, Rash ... Criteria - Fever lasting ... Polymorphous rash ... KD #vasculitis #rheumatology ... #management #treatment
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... positive patients Treatment ... Dermatomyositis #diagnosis ... #management #rheumatology
Achalasia Summary

Epidemiology: 10 cases per 100,000 individuals

Defined by inadequate relaxation of the LES and aperistalsis
Primary or
Achalasia: Testing ... The diagnosis ... Useful if manometry unclear ... #Achalasia #diagnosis ... #gastroenterology