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diagnosis differential algorithm causes management pharmacology kidney endocrinology inhibitors neurology pathophysiology diabetes table disease medications treatment visualabstract chronic dm2 euglycemic
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis: https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext #Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Pathophysiology #Mechanism #Nephrology ... #SLGT2 #Inhibitors
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... outcomes trial in SGLT2i ... mcclaffertyMD #SGLT2
SGLT2 Inhibitors and Cardiovascular Pathophysiology #SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
- Mechanism of SGLT ... Euglycemic #DKA #SGLT2
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
SGLT2 Inhibitors ... in those on an SGLT2i ... is closed • SGLT2 ... Kat_Watson #SGLT2
Indications for and pharmacological properties of approved SGLT2 inhibitors Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin #SGLT2 #Inhibitors
properties of approved SGLT2 ... Ertugliflozin #SGLT2
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
-4 inhibitors SGLT2 ... Improved outcomes in CKD
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... Kidney Disease (CKD ... /CKD • No structural ... damage #AKI #CKD ... #nephrology #acute
Stepwise Approach to Prescription of SGLT2 inhibitors Anticipatory Guidance • Consider diuretic dose reduction Patient Counseling
Prescription of SGLT2 ... endocrinologists #SGLT2
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2
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