23 results
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Antispasmodics Tricyclic antidepressants ... SSRIs #IBSD ... Bowel #Syndrome #pharmacology ... comparison #management #treatment
Neuromodulators for Disorders of Gut Brain Interactions (DGBIs)
SSRIs - When anxiety, depression, and phobic features are
Interactions (DGBIs) SSRIs ... DGBls Tetracyclic Antidepressant ... early satiety nausea ... disturbed sleep SNRls ... Neuromodulators #DGBIs #IBS #pharmacology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... Propoxyphene Other antidepressants ... Venlafaxine Tricyclic Antidepressants ... QRS #widening #ECG ... #EKG #Pharmacology
SNRls (Serotonin/Norepinephrine Reuptake Inhibitors) - FDA Approved Indications 

Venlafaxine (Effexor) - GAD, MDD, Panic Disorder, SAD
SNRls (Serotonin ... There are 5 SNRI's ... commonly used antidepressants ... clinics is for treatment ... #Indications #Pharmacology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... Allergic reaction / anaphylaxis ... syndrome (tricyclic antidepressants ... #Differential #Causes
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... treatment pack ... require prolonged treatment ... alternate vasopressor (e.g ... Anesthesiology #Anesthesia #Intraoperative
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... • Higher doses cause ... • 1st agent in anaphylaxis ... cAMP/cGMP • Causes ... Vasopressors #Inotropes #Pharmacology
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
and positioning (e.g ... ischaemia → 3-12 o Anaphylaxis ... o Endocrine cause ... (eg steroid dependency ... Anesthesiology #Anesthesia #Intraoperative
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
should identify any cause ... surgery related cause ... blood gas, 12-lead ECG ... Bronchospasm → 3-4 o Anaphylaxis ... Anesthesiology #Anesthesia #Intraoperative
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
in Anaesthesia Caused ... , e.g. central line ... pericardiocentesis kit (eg ... thoracotomy is a better treatment ... Anesthesiology #Anesthesia #Intraoperative