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liver transaminitis algorithm hepatocellular abscess apml ascites causes chemistry children cholestatic differentiation dili drug effusion enzymes function gastroenterology hepatitis idiosyncratic
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential # ... hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... Diagnosis Framework ... Drug-induced liver injury ... Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Diagnosis Framework ... Differential Diagnosis ... Diagnosis #hepatology ... Transaminitis #LFTs
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Pleural Effusion - Differential ... Diagnosis Algorithm ... Malignancy • Pulmonary ... • Postcardiac injury ... #Hepatology #causes
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis ... #LFTs #RValue #
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... coagulopathy) • CBC w differential ... pericardial effusion) • PFTs ... Renal #Syndromes #differential ... #diagnosis #management
Ascites - Diagnosis and Management Summary Paracentesis studies: cell count + differential, albumin, protein, culture • Serum-ascites-albumin-gradient
Ascites - Diagnosis ... and Management ... : cell count + differential ... #Management #Summary ... #Hepatology #SAAG
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
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