6 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... syphilis, alcohol - peripheral ... neuropathy so trauma ... #Joint #Pain #MSK ... approach #workup #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint ... pain • Swan neck ... Mononeuritis Multiplex • Peripheral ... neuropathy • Transverse
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
syndrome - SLE Neurologic ... Lyme disease • Peripheral ... neuropathy - SLE ... • Diminished peripheral ... #pain #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
glomeruli, and peripheral ... inflammation Others: • Lupus ... vesicular eruption - Joints ... such as systemic lupus ... erythematosus,
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... myopathy • Anti MAG ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Hematology #Monoclonal #Differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... affects the skin, neurologic ... ischemia • Skin: Erythematous ... vesicular eruption • Joints ... Palpable purpura, joint