4 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... #management #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
capillary leak syndrome ... myopathy • Anti MAG ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
SLE-SSc-AlM overlap syndromes ... diseases only if Ag ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... blood count with differential ... progression to AML ... #diagnosis #hematology ... #oncology