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diagnosis hematology differential algorithm oncology generalized pruritus systemic aplastic atopy common cvid dermatitis eczema eczematous hypogammaglobulinemia immunodeficiency immunology mds medications
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> AML: Blast crises ... - infiltrates (anemia ... bone marrow and secondary ... -> Invade Skin:
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... myeloid leukemia ... (CML) - Dr. ... #hematology #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
) • Atopic dermatitis ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Pruritus #primary #secondary ... #generalized #dermatology
Eczematous Skin Rash - Differential Diagnosis Algorithm Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated • Atopic Dermatitis
Eczematous Skin ... demarcated • Atopic ... lichenification (chronic ... Secondary to venous ... #Eczematous #SkinRash
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #Pruritus #secondary ... #generalized #dermatology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... (AD) is a chronic ... #management #medications ... treatment #diagnosis #causes ... #skinrash References
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Causes • Anemia ... Marrow Failure • Chronic ... Myelogenous Leukemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Damage to Marrow (Toxic ... Headaches • Pale skin ... and petechiae Causes ... virus (EBV) • Leukemia ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to impaired B-cell ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... DDX - Other causes
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