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diagnosis hematology oncology differential algorithm causes cll generalized pruritus systemic common comparison cvid hemeonc hypogammaglobulinemia immunodeficiency immunology mds myelodysplasia myelodysplastic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... #Lymphocytic #Leukemia ... #oncology #hematology ... hemeonc #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... - infiltrates (anemia ... Lymphocytic Leukemia ... bone marrow and secondary ... CLL -> Invade Skin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #CLL #Chronic ... #Lymphocytic #Leukemia
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... renal failure/uremia ... • Lymphoma • Leukemia ... Pruritus #primary #secondary ... #generalized #dermatology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
biopsy demonstrates lymphocytes ... Systemic Fibrosis: - Secondary ... large numbers of stellate ... frequent in men Chronic ... comparison #table #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #Pruritus #secondary ... #generalized #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Autoimmunity • Chronic ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... Malignancies • Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia
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