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diagnosis hematology oncology causes differential algorithm chronic cll generalized pruritus secondary aplastic atopic atopy common comparison cvid dermatitis dress eczema
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Hepatomegaly • Skin ... ’s CLL Scoring system ... • Neutropenia, anemia ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... 5) Symptoms of anemia ... marrow failure with anemia ... #hematology #hemeonc ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
): • Lymphocytes ... - infiltrates (anemia ... Leukemia): • Lymphocytes ... CLL -> Invade Skin ... #Hematology #Oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... characterized by extensive skin ... Atypical Lymphocytes ... Skin involvement ... DRESS #Syndrome #dermatology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
eosinophilia, skin ... biopsy demonstrates lymphocytes ... treatment Nephrogenic Systemic ... large numbers of stellate ... comparison #table #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Headaches • Pale skin ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... • Lymphoma • Leukemia ... Pruritus #secondary #systemic ... #generalized #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... and M panel Management ... #diagnosis #management
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... #management #medications ... dermatitis #eczema #dermatology ... #skinrash References ... corticosteroids in dermatology
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