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hematology differential causes algorithm rheumatology generalized oncology pruritus systemic agglutinin atlas basics cold common cryofibrinogenemia cvid disease hemolytic hypogammaglobulinemia immunodeficiency
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... Post-splenectomy Primary ... #Causes #hematology ... #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology ... #Differential #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... /Quantity: • Primary ... - Hemolytic anemia ... #nonpalpable #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... Secondary Cold ... anemia • Cold ... #hematology #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Abnormalities in primary ... or secondary hemostasis ... Vasculitis - Collagen disorders ... cryoglobulins • Skin ... Algorithm #Causes #dermatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
Lesions Primary ... associated with secondary ... a generalized disorder ... nettle sting #Diagnosis ... #Dermatology #Skin
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... cryoglobulinemia Associated Disorders ... Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia #diagnosis ... #rheumatology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... #Pruritus #secondary ... #generalized #dermatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... autoimmune hemolytic anemia ... and M panel Management ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... DDX: Rule Out Secondary ... Neutropenia • Platelet Disorders ... Myelodysplastic #Syndromes #diagnosis
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