16 results
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... mild normocytic anemia ... eosinophilia Primary ... : - Pale skin ... without marked anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... Post-splenectomy Primary ... #Causes #hematology ... #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology ... #Differential #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
15% of AIHA Primary ... Secondary Cold ... Secondary Cold ... anemia • Cold ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... /Quantity: • Primary ... - Hemolytic anemia ... #nonpalpable #dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... (eg, skin or esophageal ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... changes), high MCV anemia ... unclear, or if a primary ... #Differential #Diagnosis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Primary (essential ... cryoglobulinemia Associated Disorders ... Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Abnormalities in primary ... or secondary hemostasis ... Vasculitis - Collagen disorders ... cryoglobulins • Skin ... Algorithm #Causes #dermatology
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
Lesions Primary ... associated with secondary ... a generalized disorder ... nettle sting #Diagnosis ... #Dermatology #Skin