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hematology diagnosis anemia aplastic chemotherapy chronic cll cyp3a4 inducers inhibitors interactions lymphocytic management mds myelodysplasia myelodysplastic pglycoprotein syndromes table workup
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Richter’s Syndrome ... • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... #diagnosis #hematology ... #oncology
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