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diagnosis hematology oncology blood reactions anemia antinxp2 antinxp2dm aplastic chronic cll comparison dermatomyositis differential fungal infections infectiousdiseases lymphocytic mycoses scleroderma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Chronic leukemia ... nontender cutaneous plaques ... CLL -> Invade Skin ... #Hematology #Oncology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
: - Indurated plaques ... large numbers of stellate ... Disease: - Lichen planus-like ... Exposure: - Can produce ... comparison #table #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... Hepatomegaly • Skin ... macules, papules, plaques ... workup #oncology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Special Blood Product ... infections with skin ... Transfusions #diagnosis #management ... #hematology #reactions
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... virus (EBV) • Leukemia ... Anemia #oncology #hematology ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood products contain ... of transfused products ... infections with skin ... Transfusion #diagnosis #management ... #hematology #reactions
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... dissemination occurs and produces ... osteomyelitis or skin ... manifests as fixed, “plaque-like ... Fungal #Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
have typical DM skin ... Violaceous papules or plaques ... Dermatomyositis #diagnosis #management ... #rheumatology # ... dermatology
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