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diagnosis dermatomyositis differential antimda5 antinxp2 antinxp2dm chronic common distribution hematology leukemia lymphocytic management oncology photo primarycare secondary syphilis vasculitis workup
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... Physical Exam/Signs ... Hepatomegaly • Skin ... workup #oncology #hematology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
contagious of all ... Skin rash and malaise ... The signs and symptoms ... #Diagnosis #Clinical ... #Photo #Dermatology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... • Squamous cell ... macerated areas with satellite ... ; pruritis #dermatology ... #rash #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant Cell ... , mucositis • Rash ... Polyangiitis): • Eosinophilia ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... diagnosis #management #rheumatology ... #dermatology
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