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diagnosis endocrinology im 21hydroxylasedeficiency autoimmune biliary cholangitis cirrhosis clinical cullen cullensign ddxof dka emergencymedicine endo extraarticular fm genetics heatstroke hepatology
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs ... /symptoms of HHS ... hypovolemia (dry MM, skin ... seizure) #Pathophys #EM
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... blisters on the skin ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... (Xerostomia) Heart ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Bruising in the skin ... conditions that cause ... Pathophysiology: ... onset of other symptoms ... #cullensign #em
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... are not caused ... nodes: 13-15%, skin ... posterior MSK, heart ... Diagnosis #Management #Signs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Examination: • Skin
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Weight loss • Heat ... Thickening of skin ... hyperthyroidism #causes ... endocrinology #signs ... #symptoms #thyroid
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... ) • Shawl sign ... the spine) or head ... statins - probably caused
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