5 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... of Scleroderma (SSc ... thickening Signs ... #rheumatology # ... diagnosis #signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... Venous disease (SVC ... Behcet disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, PSC ... Gap #ProteinGap #differential ... #diagnosis #hematology