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hematology algorithm autoimmune biliary chronic cirrhosis classification cll disorders eosinophil eosinophilia gap globulin hepatology leukemia lymphocytic myopathy myositis oncology primary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Signs and Symptoms ... Examination: • Skin ... bile ducts Differential ... #cholangitis #diagnosis ... #workup #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... primary biliary cholangitis ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... Lymphocytosis on CBC ... #workup #oncology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... purpura: strong sign ... Lab Tests: • CBC ... #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... autoimmune hepatitis, PBC ... Gap #ProteinGap #differential ... #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... ) • Anti-Mi2 (skin ... ) • Shawl sign ... Other Diseases: • PBC ... #differential #
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