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diagnosis differential comparison dermatology inflammatory myopathies myopathy sclerosis ssc symptoms systemic workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... thickening Signs ... acro-osteolysis, myositis ... #SSc #rheumatology ... #symptoms #testing
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Scleroderma Like ... large numbers of stellate ... therefore occur in the setting ... Diagnosis #comparison #table ... #dermatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... Myositis • Onset ... diagnosis #comparison #rheumatology ... #table
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... #rheumatology #
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