9 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
likely conditions (autoimmune ... maculopapular rash, arthritis ... low ferritin, arthritis ... #rheumatology # ... diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... ) Giant cell arteritis ... Arteritis: Often ... arteritis: jaw ... #GiantCell #arteritis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
myocarditis, coronary arteritis ... SLE, Reactive arthritis ... Ocular melanoma • Arthritis ... SLE, Reactive Arthritis ... Recurrent and chronic arthritis-Azathioprine
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
early evening • Arthritis ... Arthralgias or arthritis ... maculopapular skin ... Stills #disease #AOSD ... #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... GCA (Giant Cell Arteritis ... mucositis • Rash, arthritis ... and often causes arthritis ... Glomerulonephritis, arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... and Superficial temporal ... purpura: strong sign
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Lacrimal swelling • Skin ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... disorders (RA, Temporal ... arteritis, Sarcoidosis ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... ) • Anti-Mi2 (skin ... papules and Gottron sign ... ) • Shawl sign ... • Nonerosive arthritis