11 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE, RA ... Urticarial/LCV) - Cryoglobulinemic ... #skin #dermatology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... - 10% SLE or RA ... reticularis & skin ... classification #rheumatology ... #vasculitis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... gangrenosum • IBD • RA ... Antiphospholipid-antibody syndrome • Vasculitis ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... purpura • Mixed cryoglobulinemia ... #Dermatologic ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... purpura: strong sign ... Low levels mixed cryoglobulinemia ... differential #diagnosis #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... Calciphylaxis • Cryoglobulinemia ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Immunotactoid GN & Cryoglobulinemic ... thrombosis+Pulm HTN+skin ... (Cryoglobulinemic ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... / ANCA + MPO) Cryoglobulinemic ... Skin lesions (red ... Differential #Diagnosis #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... Complications of DMARDs • Skin ... Vascular: Rheumatoid vasculitis ... Rheumatoid #Arthritis #RA ... #diagnosis #rheumatology