9 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Secondary: CTD: SLE, RA ... Vessel: Petechiae, Palpable ... - GPA Cutaneous ... #skin #dermatology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Petechiae, Palpable ... • Petechiae • Palpable ... purpura • Mixed cryoglobulinemia ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /HSP • Cryoglobulinemia ... - GPA - EGPA ... Differential #Diagnosis #hematology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Clinical triad of Palpable ... - 10% SLE or RA ... - GPA, EGPA, microscopic ... classification #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... gangrenosum • IBD • RA ... Sarcoidosis • GPA ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... Vasculitis - Skin ... purpura: strong sign ... • ANCA (Dx: GPA ... differential #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... (lupus, RA, Sjogren's ... , GPA, EGPA, Microscopic ... cryoglobulins • Skin ... Algorithm #Causes #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... MPO > PR3 60/ GPA ... / ANCA + MPO) Cryoglobulinemic ... macules, palpable ... Differential #Diagnosis #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... Immunotactoid GN & Cryoglobulinemic ... thrombosis+Pulm HTN+skin ... (Cryoglobulinemic ... Paraproteinemias #Hematology